You will design and scale biological foundation models to decode the human brain. Training 7B+ parameter models on trillions of tokens, you will bridge high-level research and production-grade systems. This role is central to developing AI that detects neurological diseases years earlier, directly translating frontier machine learning into life-changing clinical outcomes.
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Machine Learning Research Engineer at Prima Mente - Frontier Biology AI Lab
Join Prima Mente, a frontier biology AI lab, to build foundation models that decode the human brain. We are training 7B+ parameter models on 1.9T tokens using 256 H200 GPUs to detect neurological diseases years before symptoms appear. As an ML Research Engineer, you will own model architecture and low-level optimizations, bridging the gap between cutting-edge research and clinical impact. If you want to apply large-scale ML systems to the most complex challenge in biology while working alongside world-class researchers in SF or London, this is your opportunity to change the future of human health.
Overview
Role overview
Company
Primamente
Prima Mente - Frontier Biology AI Lab
Responsibilities
What you will do
- Implement high-performance ML algorithms and distributed training infrastructure optimized for massive-scale multi-omic datasets.
- Design and develop robust experimentation pipelines to enable rapid iteration, precise evaluations, and reproducible research outcomes.
- Refactor research prototypes into clean, maintainable, and performant production-grade repositories suitable for large-scale deployments.
Candidate profile
Who this is a fit for
- Extensive experience training and deploying large-scale models (7B+ parameters) with deep expertise in PyTorch, JAX, or TensorFlow.
- Strong background in low-level optimization including quantization, CUDA/Triton, and hardware-specific tuning for GPU/TPU/HPU clusters.
- Proven track record of handling massive datasets (2T+ tokens) and building scalable data processing workflows for high-throughput training.
What makes it remarkable
Why this role is remarkable
- Work at the absolute frontier of AI and biology, training 7B+ parameter models on 1.9T tokens of epigenomic data using a cluster of 256 H200 GPUs.
- Direct ownership of research direction and model architecture decisions in a flat organization where technical excellence profoundly shapes the company’s trajectory.
- Join a mission-critical lab solving the world's most complex biological system—the brain—to protect against Alzheimer's and other neurological diseases.
Jack & Jill
How Jack & Jill work together
Meet Jack
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How does this work?
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Jill is the AI recruiter working for the company. She recruits from Jack's network.
If it's a match and the company wants to meet you, they'll make the intro. In the meantime, if you'd like, Jack will send you excellent alternatives.