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Ligo Biosciences is creating next-generation tooling to manipulate chemistry and biology, starting with enzyme design. They're building computational interfaces — similar to how AlphaFold unlocked protein structure prediction — that allow both humans and AI agents to deliberately search enzyme space for new catalysts and biological interventions. The team believes enzymes are the ideal starting point: they're the programmable machinery of biology, with examples like Cas9 (which enabled CRISPR) showing how a single enzyme can revolutionize entire fields. Ligo is a small, interdisciplinary team of researchers spanning biology, chemistry, mathematics, and computer science, united by the conviction that as general intelligence becomes abundant, scientific progress will be defined by the specialized tools that let agents explore and manipulate the world. They're based in San Francisco and betting on making domains previously inaccessible to reasoning — like enzyme function — systematically designable.
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Automation Engineer at Ligo Biosciences in San Francisco, CA. Join Ligo Biosciences to design and optimize Hamilton-based workflows that advance biological research. The role offers an opportunity to grow as an early-career engineer while solving diverse technical challenges with a mission-driven team.
Research Scientist position at a confidential, well-funded biotech platform startup in San Francisco. The role focuses on assay development and high-throughput wet lab experimentation. It offers the chance to bridge computational design and physical science while helping build next-generation biological systems.
